Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats
- 2010-10
- The Journal of Microbiology 48(5)
- Ji-hee Kang
- S. Yun
- Han-Oh Park
- PubMed: 21046354
- DOI: 10.1007/s12275-010-0363-8
Study Design
- Type
- Clinical Trial
- Population
- Rats
- Methods
- In vivo experiment with rats
- Highly Cited
- Animal Study
Abstract
We investigated the weight-gain suppressive effect of Lactobacillus gasseri BNR17 isolated from human breast milk. Rats were fed a high-carbohydrate diet and administered BNR17 (BNR17 group) twice daily for twelve weeks. Changes were observed in body weight and white adipose tissue mass. The percent increase in body weight (P=0.0331) and fat pad mass (P<0.01) was significantly lower in the BNR17 group, and the FER was moderately lower (P=0.0769). These data suggest that BNR17 can prevent diet-induced overweight and may become an alternative method for treating weight problems and obesity.
Research Insights
the percent increase in body weight (P=0.0331) and fat pad mass (P<0.01) was significantly lower in the BNR17 group, and the FER was moderately lower (P=0.0769)
- Effect
- Beneficial
- Effect size
- Moderate