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Effects of Synbiotic Preparation Containing Lactobacillus gasseri BNR17 on Body Fat in Obese Dogs: A Pilot Study

  • 2022-03-03
  • Animals 12(5)
    • Han-Joon Lee
    • Jae Hyoung Cho
    • W. Cho
    • Seong-Ho Gang
    • Seung‐Hwan Park
    • B. Jung
    • H. Kim
    • K. Song


Obesity is an important health concern in humans and dogs. It can cause a variety of secondary problems, including low bacterial diversity. Several approaches have been tried to solve this problem; one of them is probiotic supplementation. Lactobacillus gasseri BNR17 is derived from breast milk and has been proven to be effective for obesity in humans. However, there have been no studies using a synbiotic preparation containing L. gasseri BNR17 for obesity management in dogs. Therefore, the present study evaluated the effectiveness of a synbiotic preparation containing L. gasseri BNR17 in reducing body fat in obese dogs. A group of obese dogs were fed a synbiotic preparation for 10 weeks. Obesity variables included body weight, body condition score, subcutaneous fat thickness, subcutaneous fat mass and proportion of the fat mass. In addition, feces collected at 0-week and 10-week time points were analyzed for the intestinal microbiome. Results showed a significant decrease in body weight, body condition score, and subcutaneous fat mass and proportion at the level of the third lumbar vertebra. Diversity and functional analysis of the microbiota in obese dogs showed increased microbial diversity, and increased abundance of metabolism of carbohydrate, and lipid after supplementation with a synbiotic preparation. This study was conducted as a pilot study, and the results demonstrated that a synbiotic preparation containing L. gasseri BNR17 may play a role in reducing body fat and resolving the obesity in dogs.

Keywords: Lactobacillus gasseri BNR17; body fat; computed tomography; microbiome; obesity; radiography.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus gasseri BNR17Improved Body Condition ScoreBeneficial
Lactobacillus gasseri BNR17Increased Microbial DiversityBeneficial
Lactobacillus gasseri BNR17Reduced Body WeightBeneficial
Lactobacillus gasseri BNR17Reduced Subcutaneous Fat MassBeneficial

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