Effects of the Consumption of Probiotic Yogurt Containing Bifidobacterium lactis Bb12 on the Levels of Streptococcus mutans and Lactobacilli in Saliva of Students with Initial Stages of Dental Caries: A Double-Blind Randomized Controlled Trial
- 2019-12-10
- Caries Research 54(1)
- A. Zare Javid
- Essam Amerian
- L. Basir
- A. Ekrami
- M. Haghighizadeh
- Leila Maghsoumi-Norouzabad
- PubMed: 31821997
- DOI: 10.1159/000504164
Abstract
Dental caries, caused by oral microbiota, is one of the most common human diseases. The present study aimed to investigate the effect of consumption of probiotic yogurt containing Bifidobacterium lactis Bb12 on salivary Streptococcus mutans and lactobacilli in students with initial stages of dental caries. In this double-blind randomized placebo-controlled clinical trial, 66 students (18-30 years) with initial stages of dental caries were selected and randomly assigned into 2 groups: the intervention group received 300 g/day of probiotic yogurt and the control group received 300 g/day of conventional yogurt for 2 weeks. An unstimulated fasting saliva sample was collected pre- and post-intervention. Bacterial counting was performed for salivary S. mutans and lactobacilli. A significant reduction in salivary S. mutans and lactobacillus counts was observed in the intervention group compared to their baseline and compared to the control group. In conclusion, it is suggested that the consumption of probiotic yogurt containing B. lactis Bb12 may modify the oral biofilm.
Keywords: Dental caries; Lactobacilli; Probiotic yogurt; Streptococcus mutans.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Bifidobacterium lactis | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis B420 | Reduced Salivary Lactobacillus Count | Beneficial | Moderate |
| Bifidobacterium lactis B420 | Reduced Salivary S. mutans Count | Beneficial | Moderate |
| Bifidobacterium lactis Bb-02 | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis Bb-02 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis BB-12 | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis BB-12 | Reduced Salivary Streptococcus Mutans Levels | Beneficial | Moderate |
| Bifidobacterium lactis Bi-07 | Reduced Oral Pathogenic Bacteria Count | Beneficial | Moderate |
| Bifidobacterium lactis BL818 | Reduced Oral Biofilm | Beneficial | Moderate |
| Bifidobacterium lactis BL818 | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis BL818 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis BLA80 | Reduced Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis BLA80 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis BLC-1 | Reduced Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis BLC-1 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis BS01 | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis BS01 | Reduced Salivary Streptococcus Mutans Levels | Beneficial | Moderate |
| Bifidobacterium lactis HA-194 | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis HA-194 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis HDS Bb-02 | Reduced Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis HDS Bb-02 | Reduced Streptococcus Mutans Levels | Beneficial | Large |
| Bifidobacterium lactis ISS Bif | Reduced Salivary Lactobacilli Levels | Beneficial | Large |
| Bifidobacterium lactis ISS Bif | Reduced Salivary Levels of Mutans Streptococci | Beneficial | Moderate |