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Efficacy of Lycium barbarum L. on plasma lipid concentration in adults: A protocol for systematic review and meta-analysis.

  • 2021-12-10
  • Medicine 100(49)
    • Xueyuan Zeng
    • Weimin Zhao
    • Yunlong Xu
    • Chengwei Zhang
    • Junliang Wu
    • Libo Xia
    • Ziyue Tian
    • Jixiang Ren

Study Design

Type
Systematic Review
Methods
Systematic review and meta-analysis of randomized controlled trials; literature search from inception to October 2021 in CNKI, PubMed, Cochrane Library, Web of Science, and Wan-fang database; two independent researchers will perform screening, extraction, quality assessment, and data analysis using Rstudio

Background

Dyslipidemia is an important risk factor for atherosclerotic cardiovascular disease. Lycium barbarum L. are widely used as medicinal and functional food and may be particularly beneficial for patients with dyslipidemia. This systematic review protocol is designed to be used to evaluate the effects of Lycium barbarum L. on plasma lipid concentration through systematic reviews and meta-analysis.

Methods

The Following electronic databases will be searched from inception to October 2021: the China National Knowledge Infrastructure, PubMed, Cochrane Library, Web of Science, and Wan-fang database. All randomized controlled trial designs evaluated the effects of Lycium barbarum L. on plasma concentrations of lipids will be included. Two researchers will operate literature retrieval, screening, information extraction, quality assessment, and data analysis independently. The analysis will be conducted using Rstudio software (Version 1.4.1717).

Results

The findings will be submitted to a peer-reviewed publication.

Conclusion

This study will provide practical and targeted evidence in investigating the impact of Lycium barbarum L. on plasma lipid concentration in adults.

Registration number

INPLASY2021110043.

Research Insights

  • goji berry→Increased High-Density Lipoprotein Cholesterol

    This systematic review protocol is designed to be used to evaluate the effects of Lycium barbarum L. on plasma lipid concentration through systematic reviews and meta-analysis.

    Effect
    Neutral
    Effect size
    Small
  • goji berry→Reduced Blood Cholesterol

    This systematic review protocol is designed to be used to evaluate the effects of Lycium barbarum L. on plasma lipid concentration through systematic reviews and meta-analysis.

    Effect
    Neutral
    Effect size
    Small
  • goji berry→Reduced LDL Cholesterol

    This systematic review protocol is designed to be used to evaluate the effects of Lycium barbarum L. on plasma lipid concentration through systematic reviews and meta-analysis.

    Effect
    Neutral
    Effect size
    Small
  • goji berry→Reduced Triglyceride Levels

    This systematic review protocol is designed to be used to evaluate the effects of Lycium barbarum L. on plasma lipid concentration through systematic reviews and meta-analysis.

    Effect
    Neutral
    Effect size
    Small
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