Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research

Study Design

Methods
Co-fermentation of B. velezensis BV702 and P. pentosaceus PP04 at ratio 1:2, 5% inoculum, 37°C for 24 h
Duration
24 h
Bacillus spp. are the main nattokinase (NK) producers, but monoculture fermentation often causes an unpleasant ammoniacal odor. This study first selected B. velezensis BV702 as a starter strain based on NK activity and sensory evaluation, and then introduced probiotic Pediococcus pentosaceus PP04 for co-fermentation to improve natto quality. The results demonstrated that under optimal conditions (strain ratio 1:2 [PP04:BV702], inoculation amount 5 %, fermentation temperature 37 °C, time 24 h), NK activity (3050 U/g) and sensory scores of natto were significantly enhanced. Mixed fermentation increased the essential amino acid content (582.79 mg/100 g) while reducing bitter amino acids. Volatilomics analysis revealed elevated levels of esters and characteristic flavor compounds (e.g., acetylpyrazine and 2-ethyl-3,5-dimethylpyrazine) in co-fermented natto. Notably, fruity, sweet, and nutty flavors intensified, whereas fatty and waxy odors diminished. This study provides insights into probiotic applications in natto production.

Research Insights

    Back to top