Evaluation of a Nutraceutical Product with Probiotics, Vitamin D, Plus Banaba Leaf Extracts (Lagerstroemia speciosa) in Glycemic Control.

2021-08-26
Endocrine, metabolic & immune disorders drug targets 21(7)
- Luca Signorini
- Andrea Ballini
- Roberto Arrigoni
- Francesco De Leonardis
- Rajiv Saini
- Stefania Cantore
- Danila De Vito
- Maria Franca Coscia
- Gianna Dipalma
- Luigi Santacroce
- Francesco Inchingolo

PubMed: 33167849
DOI: 10.2174/1871530320666201109115415

Study Design

Type: Randomized Controlled Trial (RCT)
Funding: Unclear

Background

Dysbiosis is related to changes in the composition and behaviour of intestinal microbiota, which may contribute to an age-related decline in metabolic and immune system functioning (immune-senescence).

Objective

The microbiota-targeted dietary and probiotic interventions have been shown to favorably affect the host health by an enhancement of antioxidant activity, improving immune homeostasis, suppression of chronic inflammation, regulation of metabolism and prevention of insulin resistance.

Results

In our study, the use of specific probiotics strains improved the serum concentration of glycemic markers, thereby promoting better overall health.

Conclusion

Probiotics may help correct defects in the gut microbial environment improving metabolic parameters, such as blood sugar levels, glycosylated hemoglobin and a decrease in body weight.

Research Insights

Banaba leaf→Reduced Blood Glucose Levels
such as blood sugar levels, glycosylated hemoglobin and a decrease in body weight
Effect
Beneficial
Effect size
Moderate
Banaba leaf→Reduced Body Weight
such as blood sugar levels, glycosylated hemoglobin and a decrease in body weight
Effect
Beneficial
Effect size
Moderate