Skip to main content

Exopolysaccharides produced by Pediococcus acidilactici MT41-11 isolated from camel milk: Structural characteristics and bioactive properties.

  • 2021-08
  • International Journal of Biological Macromolecules 185
    • Ying Bai
    • Baolong Luo
    • Yan Zhang
    • Xu Li
    • Zhen Wang
    • Yuqing Shan
    • Min Lu
    • F. Tian
    • Yongqing Ni


In this study, the chemical structure and bioactive properties of the EPS of Pediococcus acidilactici MT41-11 isolated from camel milk were investigated. Two polysaccharide fractions (EPS-1, EPS-2) with molecular weights about 69.0 kDa were obtained, which were purified using DEAE-Sepharose and Sephadex G-100 chromatography. Based on monosaccharide composition, FT-IR, and 1D, 2D NMR spectra, concluded that EPS-1 had a backbone composed of →2)-α-d-Manp-(1→, →3)-α-d-Manp-(1→ and with branches containing α-d-Manp-(1→, EPS-2 had a backbone composed of →6)-β-d-Glcp-(1→, and with branches containing →2)-α-l-Fucp-(1→, →3)-α-d-Glcp-(1→, →2)-α-d-Glcp-(1→, β-d-Glcp-(1→, and α-d-Glcp-(1→. Remarkably, in vitro assays showed that EPS possessed multiple bioactive properties, including stimulating Lactobacillus growth and a high DPPH free radical scavenging activity. Also, it has a good ability to anti-biofilms. Overall, the analysis of all data showed EPS from P. acidilactici MT41-11 can be used as anti-oxidant, anti-biofilm agent, and also as a potential candidate prebiotic for health food or medicine industry.

Keywords: Anti-biofilm activity; Anti-oxidant activity; Exopolysaccharides; Pediococcus acidilactici; Prebiotics.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Pediococcus acidilactici R1001Increased Antioxidant ActivityBeneficial
Pediococcus acidilactici R1001Increased Lactobacillus GrowthBeneficial
Pediococcus acidilactici R1001Reduced Biofilm FormationBeneficial

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at