Skip to main content

Abstract

Lactobacillus helveticus isolate H9 demonstrated high angiotensin I-converting enzyme (ACE)-inhibitory activity in previous research. Here, we evaluated the fermentation characteristics (pH, titratable acidity, free amino nitrogen, and viable bacterial counts), ACE-inhibitory activity, and contents of Val-Pro-Pro (VPP) and Ile-Pro-Pro (IPP) peptides of stored yogurt (4°C for 28 d) fermented by L. helveticus isolate H9 (initially inoculated at 4 concentrations), from cow, mare, and soy milks. During storage, the pH and titratable acidity remained stable in yogurts produced from all milk types and all inoculation concentrations. The viable bacterial counts in all stored yogurts ranged between 10(6.72) and 10(8.59) cfu/g. The highest ACE-inhibitory activity (70.9-74.5%) was achieved at inoculation concentrations of 5×10(6) cfu/mL. The ACE-inhibitory tripeptides VPP and IPP as determined by ultra-performance liquid chromatography-tandem mass spectrometry were not produced in yogurt made from soy milk or mare milk. These evaluations indicate that L. helveticus H9 has good probiotic properties and would be a promising candidate for production of fermented food with probiotic properties.

Keywords: Lactobacillus helveticus H9; and soy milks; angiotensin-converting enzyme; cow; fermentation characteristics; mare.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus helveticusElevated Viable Bacterial CountsBeneficial
Moderate
Lactobacillus helveticusIncreased Production of Bioactive Peptides with Angiotensin Converting Enzyme Inhibitory ActivityBeneficial
Large
Lactobacillus helveticusProduction of Probiotic PeptidesBeneficial
Large
Lactobacillus helveticus HA-128Reduced Angiotensin I-Converting Enzyme ActivityBeneficial
Large
Lactobacillus helveticus Rosell-52NDIncreased ACE Inhibitor ActivityBeneficial
Moderate

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at support@pillser.com.