Skip to main content

Gut Bifidobacteria Populations in Human Health and Aging

  • 2016-08-19
  • Frontiers in Microbiology 7
    • M. Ventura
    • S. Guglielmetti
    • S. Turroni
    • R. Ross
    • S. Arboleya
    • C. Watkins
    • C. Stanton


The intestinal microbiota has increasingly been shown to have a vital role in various aspects of human health. Indeed, several studies have linked alterations in the gut microbiota with the development of different diseases. Among the vast gut bacterial community, Bifidobacterium is a genus which dominates the intestine of healthy breast-fed infants whereas in adulthood the levels are lower but relatively stable. The presence of different species of bifidobacteria changes with age, from childhood to old age. Bifidobacterium longum, B. breve, and B. bifidum are generally dominant in infants, whereas B. catenulatum, B. adolescentis and, as well as B. longum are more prevalent in adults. Increasingly, evidence is accumulating which shows beneficial effects of supplementation with bifidobacteria for the improvement of human health conditions ranging from protection against infection to different extra- and intra-intestinal positive effects. Moreover, bifidobacteria have been associated with the production of a number of potentially health promoting metabolites including short chain fatty acids, conjugated linoleic acid and bacteriocins. The aim of this mini-review is to describe the bifidobacteria compositional changes associated with different stages in life, highlighting their beneficial role, as well as their presence or absence in many disease states.

Keywords: aging; bifidobacteria; health; intestinal microbiota; probiotics.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
BifidobacteriumEnhanced Protection Against InfectionBeneficial
Bifidobacterium bifidumEnhanced Protection Against InfectionBeneficial
Bifidobacterium bifidumIncreased Production of Bioactive MetabolitesBeneficial

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at