Health benefits, antimicrobial activities, and potential applications of probiotics: A review.

2024-12-27
Medicine 103(52)
- Amin Sepehr
- Seyedeh Tina Miri
- Shadi Aghamohammad
- Nazanin Rahimirad
- Mahnaz Milani
- Mohammad-Reza Pourshafie
- Mahdi Rohani

PubMed: 39969286
DOI: 10.1097/md.0000000000032412

Study Design

Type: Review

Gut microbiota and its metabolic activities can influence the physiology and pathology of the human body. It is well established that alterations in the balance of living microbiota can contribute to various health problems, such as inflammatory bowel disease and autoimmune disorders. Probiotics administered in sufficient quantities as functional food ingredients provide health benefits to hosts. They help to maintain the stability and composition of the gut microbiota and provide resistance to infection by pathogens. The most important probiotic bacteria are Lactobacillus spp. and Bifidobacteria spp., which protect the intestine through various mechanisms such as the production of organic acids and bacteriocins. Scientific and clinical research has demonstrated that probiotics play a role in modulating immune response and preventing cancer and chronic inflammatory diseases, especially in the gastrointestinal tract. This article summarizes the potential health benefits, antimicrobial activities, and purposes for which probiotics can be used as functional foods to improve human health.

Research Insights

Bifidobacterium breve Bb-18→Improved Gut Microbiota Balance
Probiotics administered in sufficient quantities as functional food ingredients provide health benefits to hosts. They help to maintain the stability and composition of the gut microbiota and provide resistance to infection by pathogens.
Effect
Beneficial
Effect size
Moderate
Bifidobacterium breve Bb-18→Modulated Immune Response
Scientific and clinical research has demonstrated that probiotics play a role in modulating immune response and preventing cancer and chronic inflammatory diseases, especially in the gastrointestinal tract.
Effect
Beneficial
Effect size
Moderate
Bifidobacterium breve Bb-18→Reduced Risk of Chronic Inflammatory Diseases
Scientific and clinical research has demonstrated that probiotics play a role in modulating immune response and preventing cancer and chronic inflammatory diseases, especially in the gastrointestinal tract.
Effect
Beneficial
Effect size
Moderate
Bifidobacterium breve Bb-18→Reduced Risk of Infection
They help to maintain the stability and composition of the gut microbiota and provide resistance to infection by pathogens.
Effect
Beneficial
Effect size
Moderate