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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Heavy Metal-Gut Microbiota Interactions: Probiotics Modulation and Biosensors Detection.

  • 2025-03-14
  • Biosensors 15(3)
    • Liliana Anchidin-Norocel
    • Oana C Iatcu
    • Andrei Lobiuc
    • Mihai Covasa

Study Design

Type
Review
Methods
comprehensive analysis of the complex interaction between heavy metals (HMs) and the gut microbiota, adopting a bidirectional approach
This study provides a comprehensive analysis of the complex interaction between heavy metals (HMs) and the gut microbiota, adopting a bidirectional approach that explores both the influence of HMs on the gut microbiota populations and the potential role of probiotics in modulating these changes. By examining these interconnected aspects, the study aims to offer a deeper understanding of how HMs disrupt microbial balance and how probiotic interventions may mitigate or reverse these effects, promoting detoxification processes and overall gut health. In addition, the review highlights innovative tools, such as biosensors, for the rapid, precise, and non-invasive detection of HMs in urine. These advanced technologies enable the real-time monitoring of the effectiveness of probiotic-based interventions, offering critical insights into their role in promoting the elimination of HMs from the body and improving detoxification.

Research Insights

  • These advanced technologies enable the real-time monitoring of the effectiveness of probiotic-based interventions, offering critical insights into their role in promoting the elimination of HMs from the body and improving detoxification.

    Effect
    Beneficial
    Effect size
    Moderate
  • the potential role of probiotics in modulating these changes. By examining these interconnected aspects, the study aims to offer a deeper understanding of how HMs disrupt microbial balance and how probiotic interventions may mitigate or reverse these effects, promoting detoxification processes and overall gut health.

    Effect
    Beneficial
    Effect size
    Moderate
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