Skip to main content

Hilyses®, fermented Saccharomyces cerevisiae, enhances the growth performance and skin non-specific immune parameters in rainbow trout (Oncorhynchus mykiss).

  • 2012-06
  • Fish & Shellfish Immunology 32(6)
    • N. Sheikhzadeh
    • M. Heidarieh
    • A. K. Pashaki
    • K. Nofouzi
    • Marjan Ahrab Farshbafi
    • M. Akbari


Effects of Hilyses(®), fermented Saccharomyces cerevisiae (S. cerevisiae), on growth, body composition and skin mucus immune components in rainbow trout were quantified. Ninety rainbow trout (105 ± 5 g) were randomly assigned to 2 groups in triplicates and fed dietary Hilyses(®) (5 g kg(-1)) or control diet without Hilyses(®) for 50 days. Results of this study demonstrated that growth performance increased significantly by the dietary yeast supplement; however body composition was not affected in treatment group. At the 45th and 50th day of feeding trial, results of mucus samples demonstrated that yeast supplementation in treatment group significantly promoted enzyme activities, namely lysozyme, protease, alkaline phosphatase and esterase compared to control group. Significant increases were also observed in hemagglutination and antibacterial activity against Yersinia ruckeri in fish fed treatment diet. The present study suggests that fermented S. cerevisiae may effectively promote the growth performance and skin non-specific immune parameters in rainbow trout.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Saccharomyces cerevisiae fermentateImproved Antibacterial ActivityBeneficial
Saccharomyces cerevisiae fermentateImproved Growth PerformanceBeneficial
Saccharomyces cerevisiae fermentateIncreased Mucus Enzyme Activities in SkinBeneficial

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at