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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Bacillus vallismortis acts against ginseng root rot by modifying the composition and microecological functions of ginseng root endophytes.

  • 2025-04-07
  • Frontiers in microbiology 16
    • Yang Hu
    • Liu-Yang Yang
    • Meng-Yuan Lei
    • Yi-Xin Yang
    • Zhuo Sun
    • Wan Wang
    • Zhong-Ming Han
    • Lin Cheng
    • Ze-Liang Lv
    • Mei Han
    • Li-Min Yang

Study Design

Population
ginseng root samples from a susceptible group (CK) and a biocontrol group (BIO) treated with strain SZ-4
Methods
High-throughput sequencing to examine microbial community structure; isolation and identification of endophytic bacteria HY-43 and HY-46; combination with strain SZ-4 to form bacterial consortia CS4-43 and CS4-46; evaluation of inhibitory effects against ginseng root rot

Introduction

The endophytic microbiome serves a crucial function as a secondary line of defense against pathogen invasion in plants. This study aimed to clarify the mechanism of action of the ginseng plant growth-promoting rhizobacteria (PGPR) Bacillus vallismortis SZ-4 synergizing with endophytic microorganisms in the prevention and control of root rot.

Methods

Ginseng root samples from a susceptible group (CK) with a disease level of 0-2 and a biocontrol group (BIO) treated with strain SZ-4 were collected. We employed high-throughput sequencing to examine the microbial community structure of ginseng roots at different disease levels, explore beneficial endophytic bacteria, and evaluate the efficacy of strain SZ-4 in mitigating root rot through synergistic interactions with ginseng endophytic flora.

Results

The application of the PGPR B. vallismortis SZ-4 biocontrol fungicide has been found to help ginseng resist Fusarium solani by modulating the richness and structure of endophytic microbial populations. The endophytic bacteria HY-43 and HY-46 isolated from ginseng roots treated with B. vallismortis SZ-4 were identified as Bacillus velezensis based on morphological, physiological, and biochemical characteristics, as well as 16S rDNA and gyrB sequencing analyses. The endophytic bacteria HY-43 and HY-46 were combined with strain SZ-4 to generate the bacterial consortia CS4-43 and CS4-46, respectively. Both CS4-43 and CS4-46 significantly enhanced the inhibitory effects of the single strain SZ-4, as well as HY-43 and HY-46, against ginseng root rot, while also promoting plant growth.

Discussion

These findings offers a theoretical foundation for studying the microecological prevention and control of ginseng diseases as well as new insights for conducting research on the efficient and precise management of plant diseases.

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