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Helianthus annuus Seed Extract Affects Weight and Body Composition of Healthy Obese Adults during 12 Weeks of Consumption: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.

  • 2019-05-15
  • Nutrients 11(5)
    • Aurélie Leverrier
    • David Daguet
    • Wim Calame
    • Pierre Dhoye
    • Shyam Prasad Kodimule

Study Design

Type
Randomized Controlled Trial (RCT)
Population
50 obese adults
Methods
randomly assigned to sunflower extract or isocaloric placebo groups, receiving respectively 500 mg/day of treatment for 12 weeks
Duration
12 weeks
Funding
Unclear
  • Rigorous Journal
The aim of this pilot study was to evaluate the effects of a sunflower (Helianthus annuus) seed extract, standardized for 40% chlorogenic acids on weight and body composition of obese adults. Fifty subjects were randomly assigned to sunflower extract or isocaloric placebo groups, receiving respectively 500 mg/day of treatment for 12 weeks. At the end of the intervention, a significant decrease in body weight, Body Mass Index (BMI), and waist circumference was observed, especially for obese female subjects above 30 years. Those changes were associated with modified body composition related to fat mass loss. A decrease in blood cholesterol was also observed, supporting the potential action of sunflower extract on lipid metabolism. It was concluded that consumption of sunflower extract has a beneficial effect on body weight, fat mass, and lipid profile, providing evidence for its use as a natural anti-obesity herbal extract.

Research Insights

  • sunflower→Reduced Blood Cholesterol

    A decrease in blood cholesterol was also observed

    Effect
    Beneficial
    Effect size
    Small
    Dose
    500 mg/day
  • sunflower→Reduced Body Fat Mass

    Those changes were associated with modified body composition related to fat mass loss.

    Effect
    Beneficial
    Effect size
    Small
    Dose
    500 mg/day
  • sunflower→Reduced Body Mass Index

    a significant decrease in body weight, Body Mass Index (BMI), and waist circumference was observed

    Effect
    Beneficial
    Effect size
    Small
    Dose
    500 mg/day
  • sunflower→Reduced Body Weight

    a significant decrease in body weight, Body Mass Index (BMI), and waist circumference was observed

    Effect
    Beneficial
    Effect size
    Small
    Dose
    500 mg/day
  • sunflower→Reduced Waist Circumference

    a significant decrease in body weight, Body Mass Index (BMI), and waist circumference was observed

    Effect
    Beneficial
    Effect size
    Small
    Dose
    500 mg/day
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