Landscape of Aeroallergen Sensitization in Asia.
- 2025-08-18
- Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 55(10)
- PubMed: 40820585
- DOI: 10.1111/cea.70137
Study Design
- Type
- Review
Allergic diseases caused by aeroallergens are emerging as a critical public health issue across Asia. Diverse climatic and geographic conditions play a significant role in shaping regional variation in aeroallergy sensitisation patterns across Asia. House dust mites (HDMs) remain the predominant indoor allergens, while pollen sensitisation varies substantially based on regional flora. Rapid urbanisation, evolving lifestyles, increasing air pollution, and genetic susceptibility further influence allergen exposure and sensitisation profiles. Although pharmacological and biologic therapies have advanced, allergen-specific immunotherapy (AIT) remains the only disease-modifying therapeutic strategy. This review synthesises current evidence on aeroallergen sensitisation patterns across Asia, elucidates key influencing factors across various Asian regions, and discusses current prevention and treatment strategies, emphasising the role and challenges of AIT. Improved understanding of these regional allergenic profiles and management practices is essential for developing tailored clinical guidelines and public health interventions.