Skip to main content

Physiological Characteristics and Anti-Diabetic Effect of Pediococcus pentosaceus KI62

  • 2021-03
  • Food Science of Animal Resources 41(2)
    • Seulki Kim
    • Sangpil Hong
    • Sang-Dong Lim


The purpose of this study is to examine the physiological characteristics and anti-diabetic effects of Pediococcus pentosaceus KI62. The α-amylase and α-glucosidase inhibitory activity of P. pentosaceus KI62 was 94.86±3.30% and 98.59±0.52%, respectively. In MRS broth containing 3% maltodextrin inoculated by P. pentosaceus KI62, the amounts of short chain fatty acids (SCFA) were propionic acid 18.05±1.85 mg/kg, acetic acid 1.12±0.07 g/100 mL, and butyric acid 2.19±0.061 g/kg, and those of medium chain fatty acids (MCFA) were C8 0.262±0.031 mg/kg, C10 0.279±0.021 mg/kg, and C12 0.203±0.009 mg/kg. Compared to sixteen antibiotics, P. pentosaceus KI62 had the highest sensitivity to penicillin-G and rifampicin, as well as the highest resistance to vancomycin and ampicillin. The strain also showed higher leucine arylamidase and valine arylamidase activities than other enzyme activities, but it did not produce β-glucuronidase which is carcinogenic enzymes. The survival rate of P. pentosaceus KI62 in 0.3% bile was 91.67%. Moreover, the strain showed a 98.63% survival rate in pH 2.0. P. pentosaceus KI62 exhibits resistance to Escherichia coli, Salmonella Typhimurium, Listeria monocytogenes, and Staphylococcus aureus at rates of 29.41%, 38.10%, 51.72%, and 50.47%, respectively. P. pentosaceus (23.31%) showed a similar adhesion ability to L. rhamnosus GG, the positive control (24.49%). These results show that P. pentosaceus KI62 has possibility as a probiotic with anti-diabetic effects.

Keywords: Pediococcus pentosaceus; anti-diabetic; physiological characteristics; α-amylase inhibitory activity; α-glucosidase inhibitory activity.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Pediococcus pentosaceus PP06Enhanced Probiotic Gut AdhesionBeneficial
Pediococcus pentosaceus PP06Improved Acid ToleranceBeneficial
Pediococcus pentosaceus PP06Increased Bile ToleranceBeneficial
Pediococcus pentosaceus PP06Increased Pathogen ResistanceNeutral
Pediococcus pentosaceus PP06Reduced Blood Glucose LevelsBeneficial
⬆ Back to top
Supplement Research and Comparison Website: evidence-based information about supplements, their benefits, potential risks, and their efficacy.
Receive updates about our products, services, sales, and special offers. Unsubscribe anytime. See our Privacy Policy for details on how we handle your information.

Join Our Community

Use to get in touch.