Post-COVID-19 headache- NDPH phenotype: a systematic review of case reports.

2024-05-14
Frontiers in pain research (Lausanne, Switzerland) 5
- Neetu Rani Dhiman
- Deepika Joshi
- Royana Singh
- Vyom Gyanpuri
- Anand Kumar

PubMed: 38808005
DOI: 10.3389/fpain.2024.1376506

Study Design

Type: Systematic Review
Population: patients with New Daily Persistent Headache (NDPH) after or during COVID-19 infection
Methods: Systematic review of case reports; literature search identified 3,538 articles, 12 screened, 4 case reports included

Background and objectives

Post-acute COVID-19 syndrome or "long COVID" affects patients even after the recovery from Covid infection in various ways. Persistent headache or New Daily Persistent Headache (NDPH) is one of such symptoms. In this review, we will discuss about the case-reports of post covid-19 headache- NDPH phenotype both after and in the course of COVID-19 infection.

Methods

Case reports/studies talked about patients having NDPH around the disease either immediately or late post COVID were included. Data was taken from the source and synthesised on a qualitative basis.

Results

Literature search showed 3,538 articles, out of which 12 were screened as per the eligibility criteria and finally, 4 case reports on NDPH and Covid-19 were chosen for analysis from the database and by human search. All case reports justify the criteria for acceptability in quality for this systematic review.

Conclusion

NDPH in and around Covid 19 infection is something that is currently an ingenious debated topic in the scientific community. More case studies should be written and published on the same subject so that a large systematic review could be conducted.

Trial registration information

The review is registered in Prospero with no. Identifier (CRD42022354912).

Systematic review registration

https://www.crd.york.ac.uk/, PROSPERO (CRD42022354912).