Probiotic capsules do not lower plasma lipids in young women and men
- 2007-03-14
- European Journal of Clinical Nutrition 62(2)
- K. Greany
- M. Bonorden
- Jill M. Hamilton-Reeves
- M. H. McMullen
- K. Wangen
- W. Phipps
- J. Feirtag
- W. Thomas
- M. Kurzer
- PubMed: 17356554
- DOI: 10.1038/sj.ejcn.1602719
Abstract
Objective: To investigate the effect of probiotic capsules on plasma lipids.
Design: A randomized, single-blinded, placebo-controlled, parallel-arm trial.
Subjects: Fifty-five normocholesterolemic subjects ages 18-36 (33 premenopausal women and 22 men).
Intervention: Each subject consumed either three probiotic capsules each containing a total of 10(9) colony-forming units Lactobacillus acidophilus and Bifidobacterium longum and 10-15 mg fructo-oligosaccharide or three placebo capsules daily for 2 months (men) or two menstrual cycles (women). Plasma lipids were measured before and following the intervention (during the early follicular phase for women).
Results: Plasma concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride were not altered by consumption of probiotic or placebo capsules and were not different between treatment groups following the intervention.
Conclusions: These results do not support a beneficial effect of Lactobacillus acidophilus strain DDS-1 and Bifidobacterium longum strain UABL-14 on plasma lipids in normocholesterolemic young women and men.
Sponsorship: Supported by the Minnesota Agricultural Experiment Station and UAS Laboratories.
Research Insights
Supplement | Health Outcome | Effect Type | Effect Size |
---|---|---|---|
Bifidobacterium longum UABl-14 | Unchanged Plasma Lipid Levels | Neutral | Small |