Probiotic Lactobacillus fermentum KU200060 isolated from watery kimchi and its application in probiotic yogurt for oral health.
- 2020-10
- Microbial Pathogenesis 147
- Sung-Min Lim
- N. Lee
- Kee-Tae Kim
- H. Paik
- PubMed: 32758520
- DOI: 10.1016/j.micpath.2020.104430
Abstract
Lactobacillus fermentum KU200060 was isolated from watery kimchi and its probiotic characteristics were evaluated, including tolerance to artificial gastric acid and bile salt, production of enzymes, ability to adhere to HT-29 cells, and antibiotic susceptibility. The antibacterial and antibiofilm effects of L. fermentum KU200060 against Streptococcus mutans KCTC 5316 were compared to those of Lactobacillus rhamnosus GG and Lactobacillus brevis KU15006. L. fermentum KU200060 demonstrated higher antibacterial activity and inhibition of biofilm formation by S. mutans than L. rhamnosus GG via inhibiting formation of water-insoluble glucan and related gene expression. In addition, L. fermentum KU200060 was applied as a probiotic in yogurt, and its physicochemical property and sensory value demonstrated its potential as a yogurt starter. The physicochemical characteristics and consumer acceptability of the probiotic yogurt containing L. fermentum KU200060 were not significantly different compared to those of the control yogurt. Therefore, L. fermentum KU200060 could be used for oral health in the probiotic industry.
Keywords: Anticavity activity; Oral health; Probiotic yogurt; Probiotics; Streptococcus mutans.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus fermentum | Reduced Streptococcus mutans Activity | Beneficial | Large |
| Lactobacillus fermentum | Viability as Probiotic Yogurt Starter | Beneficial | Moderate |
| Lactobacillus fermentum Lf-33 | Enhanced Gut Health | Beneficial | Moderate |
| Lactobacillus fermentum Lf-33 | Reduced Biofilm Formation | Beneficial | Large |
| Lactobacillus fermentum Lf-33 | Reduced Streptococcus mutans Activity | Beneficial | Large |
| Lactobacillus fermentum LF61 | Improved Antibacterial Activity | Beneficial | Large |
| Lactobacillus fermentum LF61 | Improved Oral Health | Beneficial | Large |
| Lactobacillus fermentum MAK20L13F | Increased Consumer Acceptability of Probiotic Yogurt | Neutral | Small |
| Lactobacillus fermentum MAK20L13F | Reduced Biofilm Formation | Beneficial | Large |
| Lactobacillus fermentum MAK20L13F | Reduced Streptococcus mutans Activity | Beneficial | Large |
| Lactobacillus fermentum UALf-32 | Potential Probiotic Benefits | Beneficial | Large |
| Lactobacillus fermentum UALf-32 | Reduced Streptococcus mutans Activity | Beneficial | Large |
| Lactobacillus fermentum VPro 14 | Reduced Mutans Streptococcus Counts | Beneficial | Large |
| Lactobacillus fermentum VPro 14 | Suitability as a Probiotic Yogurt Starter | Beneficial | Moderate |