Probiotics as an adjunctive therapy in periodontitis treatment-reality or illusion-a clinical perspective.
- 2024-12-16
- NPJ biofilms and microbiomes 10(1)
- PubMed: 39681550
- DOI: 10.1038/s41522-024-00614-5
Study Design
- Type
- Review
- Population
- forty clinical studies
- Methods
- This review examines probiotics as adjunctive therapy for periodontitis by analyzing forty clinical studies.
Periodontitis, a prevalent oral health issue, involves various microorganisms and clinical effects. This review examines probiotics as adjunctive therapy for periodontitis by analyzing forty clinical studies. Findings showed mixed results due to differences in study design, probiotic types, and clinical parameters; however, probiotics improved outcomes in severe cases. Caution is advised when interpreting these results, as longer follow-up periods reveal variability and potential regression in effects.
Research Insights
| Supplement | Dose | Health Outcome | Effect Type | Effect Size | Source |
|---|---|---|---|---|---|
| Lactobacillus reuteri SD-5865 | — | Improved Periodontal Health | Beneficial | Small | View sourceFindings showed mixed results due to differences in study design, probiotic types, and clinical parameters; however, probiotics improved outcomes in severe cases. |