Probiotics: Protecting Our Health from the Gut.

2022-07-14
Microorganisms 10(7)

PubMed: 35889147
DOI: 10.3390/microorganisms10071428

Study Design

Type: Review

The gut microbiota (GM) comprises billions of microorganisms in the human gastrointestinal tract. This microbial community exerts numerous physiological functions. Prominent among these functions is the effect on host immunity through the uptake of nutrients that strengthen intestinal cells and cells involved in the immune response. The physiological functions of the GM are not limited to the gut, but bidirectional interactions between the gut microbiota and various extraintestinal organs have been identified. These interactions have been termed interorganic axes by several authors, among which the gut-brain, gut-skin, gut-lung, gut-heart, and gut-metabolism axes stand out. It has been shown that an organism is healthy or in homeostasis when the GM is in balance. However, altered GM or dysbiosis represents a critical factor in the pathogenesis of many local and systemic diseases. Therefore, probiotics intervene in this context, which, according to various published studies, allows balance to be maintained in the GM, leading to an individual's good health.

Research Insights

Supplement	Dose	Health Outcome	Effect Type	Effect Size	Source
Lactobacillus brevis SBC8803	—	Improved Tolerance	Beneficial	Moderate	View source The probiotic group reported significantly better cold tolerance than the placebo group, especially in females.
Lactobacillus brevis SBC8803	—	Reduced Fat Accumulation	Beneficial	Moderate	View source Consumption of Lactobacillus brevis SBC8803 significantly suppressed body fat accumulation compared with placebo in healthy adults.