Recent Progress in Applicability of Exercise Immunology and Inflammation Research to Sports Nutrition.

2021-11-28
Nutrients 13(12)
- Katsuhiko Suzuki

PubMed: 34959851
DOI: 10.3390/nu13124299

Study Design

Type: Review

Rigorous Journal

This article focuses on how nutrition may help prevent and/or assist with recovery from the harmful effects of strenuous acute exercise and physical training (decreased immunity, organ injury, inflammation, oxidative stress, and fatigue), with a focus on nutritional supplements. First, the effects of ketogenic diets on metabolism and inflammation are considered. Second, the effects of various supplements on immune function are discussed, including antioxidant defense modulators (vitamin C, sulforaphane, taheebo), and inflammation reducers (colostrum and hyperimmunized milk). Third, how 3-hydroxy-3-methyl butyrate monohydrate (HMB) may offset muscle damage is reviewed. Fourth and finally, the relationship between exercise, nutrition and COVID-19 infection is briefly mentioned. While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.

Research Insights

Colostrum→Reduced Inflammation
inflammation reducers (colostrum and hyperimmunized milk)
Effect
Neutral
Effect size
Small
Pau d'Arco→Reduced Oxidative Stress
antioxidant defense modulators (vitamin C, sulforaphane, taheebo)
Effect
Neutral
Effect size
Small
Vitamin C→Reduced Oxidative Stress
antioxidant defense modulators (vitamin C, sulforaphane, taheebo)
Effect
Neutral
Effect size
Small

Adverse Events Reported

Colostrum→Overall tolerability
While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.
Finding
Reported
Vitamin C→Overall tolerability
While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.
Finding
Reported
Pau d'Arco→Overall tolerability
While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.
Finding
Reported