Skip to main content

Reducing the risk of infection in the elderly by dietary intake of yoghurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1

  • 2010-05-21
  • British Journal of Nutrition 104(7)
    • Seiya Makino
    • S. Ikegami
    • Akinori Kume
    • H. Horiuchi
    • H. Sasaki
    • Naoki Orii

Abstract

Immune senescence potentially leads to an increased risk of infections. It is desirable to augment the immune system and protect against infections by daily consumption of immunostimulatory food. The present study evaluated whether the intake of yoghurt fermented with Lactobacillus delbrueckii ssp. bulgaricus (L. bulgaricus) OLL1073R-1 has an effect on resistance to the common cold. We conducted two independent studies, in which fifty-seven (median age 74.5 years) and eighty-five healthy elderly individuals (median age 67.7 years) were participants. In each study, the subjects were divided into two groups based on age and sex and instructed to eat 90 g yoghurt or drink 100 ml milk once per d over an 8- or 12-week period. A meta-analysis of the results of these two independent studies showed the risk of catching the common cold was about 2.6 times lower (OR 0.39; P = 0.019) in the yoghurt group than in the milk group and the increase of natural killer cell activity was significantly higher in the yoghurt group than in the milk group (P = 0.028). In addition, the quality of life score for the 'eye/nose/throat' system after intake was significantly higher in the yoghurt group than in the milk group and the improvement of the score was correlated with the promotion of natural killer cell activity. In conclusion, consumption of yoghurt fermented with L. bulgaricus OLL1073R-1 augmented natural killer cell activity and reduced the risk of catching the common cold in elderly individuals.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus bulgaricusImproved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus bulgaricusImproved Quality of Life for Eye, Nose, and Throat SymptomsBeneficial
Moderate
Lactobacillus bulgaricusReduced Risk of Common ColdBeneficial
Moderate
Lactobacillus bulgaricus LB42Improved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus bulgaricus LB42Improved Quality of Life for Eye, Nose, and Throat SymptomsBeneficial
Moderate
Lactobacillus bulgaricus LB42Reduced Risk of Common ColdBeneficial
Moderate
Lactobacillus bulgaricus Lb-87Improved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus bulgaricus Lb-87Improved Quality of Life for Eye, Nose, and Throat SymptomsBeneficial
Moderate
Lactobacillus bulgaricus Lb-87Reduced Risk of Common ColdBeneficial
Moderate
Lactobacillus bulgaricus SD-6833Improved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus bulgaricus SD-6833Improved Quality of Life for Eye HealthBeneficial
Moderate
Lactobacillus bulgaricus SD-6833Reduced Risk of Common ColdBeneficial
Moderate
Lactobacillus delbrueckiiImproved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus delbrueckiiImproved Quality of Life for Eye, Nose, and Throat SymptomsBeneficial
Moderate
Lactobacillus delbrueckiiReduced Risk of Common ColdBeneficial
Moderate
Lactobacillus delbrueckii subsp. bulgaricus UALb-15Improved Natural Killer Cell ActivityBeneficial
Moderate
Lactobacillus delbrueckii subsp. bulgaricus UALb-15Improved Quality of Life for Eye, Nose, and Throat SymptomsBeneficial
Moderate
Lactobacillus delbrueckii subsp. bulgaricus UALb-15Reduced Risk of Common ColdBeneficial
Moderate
⬆ Back to top
Pillser
Supplement Research and Comparison Website: evidence-based information about supplements, their benefits, potential risks, and their efficacy.
Receive updates about our products, services, sales, and special offers. Unsubscribe anytime. See our Privacy Policy for details on how we handle your information.

Join Our Community

Use support@pillser.com to get in touch.