Research progress on extraction, processing technology and pharmacological action of Polygonatum polysaccharides: A review.
- 2026-03
- International journal of biological macromolecules 352
- Weiyi Zhao
- Lingzhuo An
- Hongyue Tian
- Xia Li
- Wenyuan Gao
- PubMed: 41655917
- DOI: 10.1016/j.ijbiomac.2026.150808
Study Design
- Type
- Review
The genus Polygonatum is distributed throughout the temperate northern hemisphere and has been widely used worldwide as a food and medicinal ingredient. Polysaccharides are an important active component in Polygonatum. More and more studies have shown that Polygonatum has a wide range of biological functions. In this paper, we reviewed the latest progress of extraction, separation, structure, biological activity, and structure-activity relationship of Polygonum polysaccharides, especially the influence of various processing methods on the structure-activity of Polygonatum polysaccharides, such as nine steaming and nine drying, wine-processed, honey-processed, and other processing methods. Different processing methods would lead to differences in structure and the various biological activities of polysaccharides. In addition, we also discussed the product development and application prospects of Polygonatum polysaccharides in pharmaceutical, food, cosmetics, and materials fields, discussed the challenges and prospects of fruit polysaccharides research, and laid a theoretical foundation for the further development and application of Polygonatum polysaccharides in nutrition and medicine fields.