Review of potential anti-cancer properties of lactobacilli against breast cancer.
- 2025-06-03
- Future oncology (London, England) 22(5)
- Elnaz Ghorbani
- Asma Afshari
- Amir Avan
- Majid Khazaei
- Saman Soleimanpour
- PubMed: 40459043
- DOI: 10.1080/14796694.2024.2438594
Study Design
- Type
- Review
Breast cancer is one of the leading cause of mortality among females worldwide. Regarding the side effects of current therapeutics, the development of novel target-specific treatments is a priority. Probiotic bacteria, as nutraceuticals, have shown anti-cancer potential, supported by cell culture-based and animal model studies. There are studies indicating differences in gut and breast microbiota between healthy individuals and cancerous patients. Given the immunomodulatory and regulatory effects of probiotics on hormone-mediated pathways, the consumption of probiotics can be considered a safe approach in breast cancer management. This review summarizes the recent research on the potential therapeutic roles of Lactobacillus strains in breast cancer.