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Summary of Probiotic Activities of Bifidobacterium lactis HN019

  • 2006-10
  • Journal of Clinical Gastroenterology 40(9)
    • M. Sanders

Abstract

The bacterium, Bifidobacterium lactis HN019, has been studied for a variety of traits important to its ability to function as a probiotic. Publications documenting identity, safety, antipathogenic effects, immune enhancement, and intestinal colonization are reviewed. Most studies documenting immune effects are short term in duration (< or =6 wk feeding periods), so longer term trials would be useful to determine to what extent effects are sustained. One year-long trial feeding both galacto-oligosaccharides and HN019 in children 1 to 3 years of age provided evidence for improved growth and reduction in infection incidence. HN019 is a well-characterized probiotic strain with documented probiotic effects of meaningful magnitude especially in the area of immune system modulation.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bifidobacterium animalis subsp. lactis HN019Enhanced Immune System FunctionBeneficial
Moderate
Bifidobacterium animalis subsp. lactis HN019Improved Growth in ChildrenBeneficial
Large
Bifidobacterium animalis subsp. lactis HN019Reduced Incidence of InfectionsBeneficial
Large
Bifidobacterium lactis BS01Improved Growth in ChildrenBeneficial
Large
Bifidobacterium lactis BS01Modulated Immune ResponseBeneficial
Moderate
Bifidobacterium lactis BS01Reduced Incidence of InfectionsBeneficial
Large
Bifidobacterium lactis HN019Improved Growth in ChildrenBeneficial
Large
Bifidobacterium lactis HN019Modulated Immune ResponseBeneficial
Moderate
Bifidobacterium lactis HN019Reduced Incidence of InfectionsBeneficial
Large
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