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Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

  • 2001-05-01
  • Journal of Antimicrobial Chemotherapy 47(5)
    • Ichiko Sakamoto
    • M. Igarashi
    • Katsunori Kimura
    • Atsushi Takagi
    • Takeshi Miwa
    • Yasuhiro Koga

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus gasseriReduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseriSuppressed Helicobacter pyloriBeneficial
Large
Lactobacillus gasseri KS-13Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri KS-13Suppressed H. Pylori InfectionBeneficial
Large
Lactobacillus gasseri LAC-343Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri LAC-343Suppressed Helicobacter pyloriBeneficial
Large
Lactobacillus gasseri LBV 150NReduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri LBV 150NSuppressed Helicobacter pyloriBeneficial
Large
Lactobacillus gasseri LG-36Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri LG-36Suppressed Helicobacter pyloriBeneficial
Large
Lactobacillus gasseri LQ-36Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri LQ-36Suppressed H. Pylori InfectionBeneficial
Large
Lactobacillus gasseri SD-5585Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri SD-5585Reduced H. pylori InfectionBeneficial
Large
Lactobacillus gasseri UALg-05Reduced Gastric Mucosal InflammationBeneficial
Large
Lactobacillus gasseri UALg-05Suppressed Helicobacter pyloriBeneficial
Large
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