Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.
- 2001-05-01
- Journal of Antimicrobial Chemotherapy 47(5)
- Ichiko Sakamoto
- M. Igarashi
- Katsunori Kimura
- Atsushi Takagi
- Takeshi Miwa
- Yasuhiro Koga
- PubMed: 11328791
- DOI: 10.1093/JAC/47.5.709
Abstract
To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus gasseri | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri | Suppressed Helicobacter pylori | Beneficial | Large |
| Lactobacillus gasseri KS-13 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri KS-13 | Suppressed H. Pylori Infection | Beneficial | Large |
| Lactobacillus gasseri LAC-343 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri LAC-343 | Suppressed Helicobacter pylori | Beneficial | Large |
| Lactobacillus gasseri LBV 150N | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri LBV 150N | Suppressed Helicobacter pylori | Beneficial | Large |
| Lactobacillus gasseri LG-36 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri LG-36 | Suppressed Helicobacter pylori | Beneficial | Large |
| Lactobacillus gasseri LQ-36 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri LQ-36 | Suppressed H. Pylori Infection | Beneficial | Large |
| Lactobacillus gasseri SD-5585 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri SD-5585 | Reduced H. pylori Infection | Beneficial | Large |
| Lactobacillus gasseri UALg-05 | Reduced Gastric Mucosal Inflammation | Beneficial | Large |
| Lactobacillus gasseri UALg-05 | Suppressed Helicobacter pylori | Beneficial | Large |