The Application Prospects and Future Outlook of Kadsura coccinea (Lem). A.C.Sm. in Rheumatoid Arthritis.
- 2026-02-11
- Drug design, development and therapy 20
- Fan Ouyang
- Xiuli Xi
- Yun Liang
- Min Wang
- Mei Liu
- Xiaoyan Jin
- Hui Li
- Jianxin Liu
- Xuguang Hu
- PubMed: 41710579
- DOI: 10.2147/dddt.s569093
Study Design
- Type
- Review
Kadsura coccinea (Lem). A.C.Sm. has a long history of use in traditional Dong medicine for activating Qi, relieving pain, and dispersing blood stasis. It has garnered increasing attention for treating rheumatoid arthritis (RA), a condition associated with synovial inflammation and tissue damage. K. coccinea L. effects anti-RA by eliminating reactive oxygen species and directly or indirectly inhibiting lipid peroxidation. This review summarizes its potential therapeutic effects on RA through regulating inflammatory cytokines, reducing oxidative stress, and targeting specific cells and pathways, forecasting its future application prospects.