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The Effects of Yacon Consumption on Body Weight and C-reactive Protein: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

  • 2026-06
  • Current therapeutic research, clinical and experimental 104
    • Fariborz Porbafrani
    • Mohammad Samadi
    • Karim Parastouei

Study Design

Type
Review
Sample size
n = 246
Population
adults
Methods
Meta-analysis of randomized controlled trials, searching PubMed/Medline, Scopus, Web of Science, and Google Scholar until June 2024, including 7 studies with 246 participants, using random-effects model

Background

The rising global challenges of obesity and chronic inflammation contribute to an increased prevalence of metabolic disorders and cardiovascular diseases.

Objective

The goal of the meta-analysis of randomized controlled trials (RCTs) was to assess the impact of yacon consumption on body weight and levels of C-reactive protein (CRP).

Methods

Online databases such as PubMed/Medline, Scopus, Web of Science, and Google Scholar were searched until June 2024 to collect RCTs that investigated the impact of yacon consumption on body weight and CRP. Meta-analyses were conducted using a random-effects model, and the I2 index was employed to evaluate the heterogeneity among the RCTs.

Results

Seven studies with a total of 246 participants were included in the study. The pooled effect size indicated that yacon intake was associated with weight reduction (weighted mean difference [WMD], -8.22 kg; 95% CI, -16.01 to -0.43; P = .039). In contrast, yacon consumption showed no significant effects on body mass index (BMI) (WMD, -1.48 kg/m2; 95% CI, -4.11 to 1.14; P = .268), waist circumference (WC) (WMD, -3.73 cm; 95% CI, -10.18 to 2.72; P = .257), and CRP (WMD, -0.07 mg/L; 95% CI, -1.96 to 1.81; P = .939). Subgroup analyses demonstrated that yacon consumption led to significant weight reductions in individuals aged 40 years and older, as well as in women and those who consumed yacon for more than 8 weeks. Additionally, yacon consumption was associated with reductions in BMI and WC in women and individuals aged >40 years. However, no statistically significant differences were observed for other factors.

Conclusions

The findings suggest that yacon consumption may contribute to weight reduction in adults, though effects on BMI, WC, and CRP remain uncertain.

Research Insights

  • Yacon→Reduced Body Mass Index

    yacon consumption showed no significant effects on body mass index (BMI) (WMD, -1.48 kg/m²; 95% CI, -4.11 to 1.14; P = .268)

    Effect
    Neutral
    Effect size
    Small
  • Yacon→Reduced Body Weight

    The pooled effect size indicated that yacon intake was associated with weight reduction (weighted mean difference [WMD], -8.22 kg; 95% CI, -16.01 to -0.43; P = .039).

    Effect
    Beneficial
    Effect size
    Large
  • Yacon→Reduced C-Reactive Protein Levels

    yacon consumption showed no significant effects on ... CRP (WMD, -0.07 mg/L; 95% CI, -1.96 to 1.81; P = .939)

    Effect
    Neutral
    Effect size
    Small
  • Yacon→Reduced Waist Circumference

    yacon consumption showed no significant effects on ... waist circumference (WC) (WMD, -3.73 cm; 95% CI, -10.18 to 2.72; P = .257)

    Effect
    Neutral
    Effect size
    Small
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