Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells.
- 2012-12
- Journal of Bioscience and Bioengineering 114(6)
- S. Yanagihara
- Tatsuhiko Hirota
- N. Yamamoto
- PubMed: 22841868
- DOI: 10.1016/j.jbiosc.2012.07.001
Abstract
Transcriptome analysis showed that Lactobacillus acidophilus L-92 cells having anti-allergy effects on human up-regulated 41 genes involved permease, ABC transporter, proteinase and transcriptional regulator after attached to epithelial Caco-2 cells. Inversely, 37 genes were down-regulated, including ATP synthases, ABC transporters and transcriptional regulators.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus acidophilus L-92 | Reduced Allergy Symptoms | Beneficial | Moderate |