Update on novel acne treatments: a narrative review focused on microbiome modulation and non-pharmacological approaches.
- 2026-01
- Anais brasileiros de dermatologia 101(1)
- Valentina Burckhardt-Bravo
- Rodrigo Funes-Ferrada
- Fernando Valenzuela
- PubMed: 41544313
- DOI: 10.1016/j.abd.2025.501249
Study Design
- Type
- Review
- Methods
- This narrative review explores recent advances in non-pharmacological acne treatments, focusing on various microbiome modulation strategies.
Acne vulgaris is a chronic inflammatory condition with multifactorial pathogenesis. Despite the availability of numerous treatment options, there remains a need for safe, well-tolerated, and microbiome-preserving therapies. This narrative review explores recent advances in non-pharmacological acne treatments, focusing on various microbiome modulation strategies. It highlights emerging therapeutic modalities and their potential impact on clinical practice. Key findings from recent studies are summarized, providing insights for future research and practical applications in dermatology.
Research Insights
In the context of microbiome modulation strategies, the review highlights emerging therapeutic modalities and their potential impact on clinical practice, including findings related to novel acne treatments such as Lactobacillus casei LC03.
- Effect
- Beneficial
- Effect size
- Moderate