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Vitamin C-Based Gingival Depigmentation Versus Surgical Depigmentation: A Randomized Clinical Trial.

  • 2024-01
  • TheScientificWorldJournal 2024(1)
    • Aehad Ul Haque
    • Nand Lal
    • Shalini Kaushal
    • Pavitra Rastogi
    • Rameshwari Singhal

Study Design

Type
Randomized Controlled Trial (RCT)
Population
Forty-two patients presenting with ethnicity-related hyperpigmentation
Methods
Randomly divided into two groups, Group I (n=21) treated with locally injected vitamin C and Group II (n=21) treated by surgical depigmentation
Background: This study aimed at comparing gingival depigmentation by locally injected vitamin C with surgical depigmentation, in terms of effectiveness and patient acceptability. Methods: Forty-two patients presenting with ethnicity-related hyperpigmentation were randomly divided into two groups, Group I (n = 21) was treated with locally injected vitamin C and Group II (n = 21) was treated by surgical depigmentation. The outcome was assessed using Gingival Pigmentation Index (GPI) and Skin Hyperpigmentation Index (SHI). Results: Both the techniques were successful in treating gingival hyperpigmentation, but the patients who underwent vitamin C-based depigmentation showed significantly higher satisfaction with the treatment result, based on patient reported Visual Analog Scale (VAS) scoring. Conclusion: Based on the findings of this study, it was concluded that locally injected vitamin C and surgical depigmentation are comparable in their effectiveness for treating gingival hyperpigmentation. Trial Registration: ClinicalTrials.gov identifier: CTRI/2023/02/050127.

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