Retinoids in cancer chemoprevention and therapy: Meta-analysis of randomized controlled trials.
- 2022-11-09
- Systematic Review · n = 627
- Frontiers in genetics 13
- Shuting Chen
- Qinchao Hu
- Xiaoan Tao
- Juan Xia
- Tong Wu
- Bin Cheng
- Juan Wang
- PubMed: 36437918
- DOI: 10.3389/fgene.2022.1065320
- High evidence
- Clinical
Our results showed that lower recurrence rate and better clinical response were obtained in retinoids treated patients with cancer or premalignancy as compared with control. The differences were statistically significant (RR = 1.24, 95% CI = 1.03-1.49, p = 0.02
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes