The Utility of Oral Vitamin B1 and Mecobalamin to Improve Corneal Nerves in Dry Eye Disease: An In Vivo Confocal Microscopy Study.
- 2022-09-11
- RCT · n = 199
- Nutrients 14(18)
- Xiaotong Ren
- Yilin Chou
- Yuexin Wang
- Dalan Jing
- Yanyan Chen
- Xuemin Li
- PubMed: 36145126
- DOI: 10.3390/nu14183750
- High evidence
- Large Human Trial
- Rigorous Journal
- Clinical
symptoms of dryness, pain, photophobia, blurred vision, total symptom score, and OSDI at 1/3 months post-treatment (all p < 0.05).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes