gestational diabetesIncreased risk
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal intrauterine growth restrictionIncreased risk
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal low birthweightIncreased risk
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal low gestational ageIncreased risk
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal miscarriageIncreased riskSerious adverse event
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal neural tube defectsIncreased riskSerious adverse event
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal pre-eclampsiaIncreased risk
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal preterm birthIncreased riskSerious adverse event
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal spontaneous abortionIncreased riskSerious adverse event
Deficiencies in vitamin B12 are linked with several negative maternal and fetal health outcomes including pre-eclampsia, gestational diabetes, spontaneous abortion/miscarriage, preterm birth, neural tube defects, intrauterine growth restriction, and low gestational age and birthweight.
from: Exploring the Impact of Folic Acid Supplementation and Vitamin B12 Deficiency on Maternal low birthweightNo significant differenceRR 1.50, 95% CI 0.93 to 2.43; 2 trials, 344 women
low birthweight (RR 1.50, 95% CI 0.93 to 2.43; 2 trials, 344 women; low-certainty evidence)
from: Vitamin B12 supplementation during pregnancy for maternal and child health outcomes.maternal anaemiaNo significant differenceRR 1.08, 95% CI 0.93 to 1.26
there may be little to no difference for maternal anaemia by intervention group, but the evidence is very uncertain (70.9% versus 65.0%; risk ratio (RR) 1.08, 95% CI 0.93 to 1.26; 2 trials, 284 women; very low-certainty evidence).
from: Vitamin B12 supplementation during pregnancy for maternal and child health outcomes.preterm birthNo significant differenceRR 0.97, 95% CI 0.55 to 1.74; 2 trials, 340 women
the evidence is uncertain about the effect on adverse pregnancy outcomes, including preterm birth (RR 0.97, 95% CI 0.55 to 1.74; 2 trials, 340 women; low-certainty evidence)
from: Vitamin B12 supplementation during pregnancy for maternal and child health outcomes.spontaneous abortionReported
Two trials reported data on spontaneous abortion (or miscarriage); however, the trials did not report quantitative data for meta-analysis and there was no clear definition of spontaneous abortion in the study reports.
from: Vitamin B12 supplementation during pregnancy for maternal and child health outcomes.