Vitamin B12 and Reduced Tinnitus Severity

• The effect of vitamin B12 on idiopathic tinnitus.

  • 2024-01
  • RCT · n = 140
  • American journal of otolaryngology 45(1)
  • • Mohammadhossein Dadgarnia
    • Mohammad Mandegari
    • Vahid Zand
    • Sedighe Vaziribozorg
    • Hadi Zare-Zardini
    • Kimia Mousaviyazdi
    • Mohammadali Kheradmandi

  • PubMed: 37647778
  • DOI: 10.1016/j.amjoto.2023.104028

  1 Insight on

  • Reduced Tinnitus Severity

  • High evidence
  • Large Human Trial
  • Clinical

  According to VAS score, there was no significant statistical differences in tinnitus severity in each group (B12 group, p.value = 0.851 and placebo group, p.value = 0.386). There was no significant statistical differences in tinnitus severity based on VAS score between two groups before the participation (p.value = 0.560), one month (p.value = 0.485) and three months (p.value = 0.254) after the participation. According to THI criterion, there was no significant statistical differences in tinnitus severity in each group (B12 group, p.value = 0.259 and placebo group, p.value = 0.521). There was no significant statistical differences in tinnitus severity based on THI score between two groups before the participation (p.value = 0.651), one month (p.value = 0.125) and three months (p.value = 0.089) after the participation.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No