Vitamin B2 and Increased Adverse Events

• Riboflavin supplements for blood pressure lowering in adults.

  • 2025-10-22
  • Meta-Analysis · n = 320
  • The Cochrane database of systematic reviews 2025(10)
  • • Kathryn E Bradbury
    • Sean Coffey
    • Nikki Earle
    • Cliona Ni Mhurchu
    • Andrew B Jull

  • PubMed: 41123035
  • DOI: 10.1002/14651858.cd015464.pub2

  3 Insights on

  • Increased Adverse Events

  • High evidence
  • Adults

  there were two adverse events in the riboflavin group and one in the control group. Low-certainty evidence suggests that riboflavin may result in little to no difference in adverse events.

  Effect

  Neutral

  Effect size

  Small