Effects of nicotinamide supplementation in normal-tension glaucoma: a crossover placebo-controlled randomised clinical trial.
- 2025-10-30
- RCT
- The British journal of ophthalmology 110(4)
- Ahnul Ha
- Young Kook Kim
- Chang Kyu Lee
- Pete A Williams
- James E Morgan
- Young In Shin
- Eunsol Kim
- Myungjin Kim
- Seungsoo Rho
- PubMed: 41167798
- DOI: 10.1136/bjo-2025-328096
- High evidence
- Clinical
After 12 weeks, the amplitude changes of the photopic negative response in peak-to-trough (PhNRPT) ... were significantly greater in the NAM group (3.121±3.968 μV) compared with the placebo group (0.996±4.190 μV; p=0.045).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 1 g/day for 6 weeks, then 2 g/day for 6 weeks