Vitamin B3 and Improved Visual Field Mean Deviation

Doses used in studies

g/day: 1.5–3 (median 2.25, IQR 1.5–3) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 1 study

1 of 1 paper

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

2020-07-28
RCT
Clinical & experimental ophthalmology 48(7)
- Flora Hui
- Jessica Tang
- Pete A Williams
- Myra B McGuinness
- Xavier Hadoux
- Robert J Casson
- Michael Coote
- Ian A Trounce
- Keith R Martin
- Peter van Wijngaarden
- Jonathan G Crowston

PubMed: 32721104
DOI: 10.1111/ceo.13818

2 Insights on

Improved Visual Field Mean Deviation

High evidence
Highly Cited
Clinical

A trend for improved visual field mean deviation was observed with 27% improving ≥1 dB on nicotinamide and fewer deteriorating (4%) compared to placebo (P = .02).

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 1.5 g/day then 6 weeks of 3.0 g/day