Absorption, anti-inflammatory, antioxidant, and cardioprotective impacts of a novel fasting mimetic containing spermidine, nicotinamide, palmitoylethanolamide, and oleoylethanolamide: A pilot dose-escalation study in healthy young adult men.
- 2024-12
- RCT
- Nutrition research (New York, N.Y.) 132
- Christopher H Rhodes
- Brian V Hong
- Xinyu Tang
- Cheng-Yu Weng
- Jea Woo Kang
- Joanne K Agus
- Carlito B Lebrilla
- Angela M Zivkovic
- PubMed: 39549554
- DOI: 10.1016/j.nutres.2024.10.006
- High evidence
- Adults
Plasma 1-methylnicotinamide, PEA, and OEA concentrations increased after supplement intake (P < .05).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- low, medium, or high doses (specific doses not stated in abstract)