Vitamin B3 and Reduced Risk of Peripheral Vascular Disease

• Decreased risk of cardiovascular disease in dermatology patients taking niacinamide: A TriNetX cohort study.

  • 2026-03
  • Observational · n = 3,231
  • Journal of the American Academy of Dermatology 94(3)
  • • Yousef Salem
    • Mahnoor Liaqat
    • Nadeen Gonna
    • Dina Zamil
    • Ferris Abu-Ghosh
    • Anwar Merie
    • Dimitri Cassimatis
    • Ida Orengo

  • PubMed: 41177359
  • DOI: 10.1016/j.jaad.2025.10.115

  3 Insights on

  • Reduced Risk of Peripheral Vascular Disease

  • High evidence
  • Clinical

  Niacinamide use was associated with reduced risk of ... peripheral vascular disease (RR: 0.741, 95% CI: 0.605-0.909, P = .004)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  ≥500 mg