Vitamin B3 and Reduced Squamous Cell Carcinoma

• An Umbrella Review on the Prevention of Skin Diseases: Do Specific Nutrients Play a Protective Role?

  • 2026-02-28
  • Review · n = 229
  • Preventive nutrition and food science 31(1)
  • • Giuseppa Granvillano
    • Michelangelo Mercogliano
    • Andrea Vecchietti
    • Giuseppa Minutolo
    • Camilla Lugli
    • Paolo Strano
    • Martina Chimienti
    • Marzia Pellegrini
    • Giovanni Leonardo Briganti
    • Gloria Spatari
    • Francesco Leonforte
    • Teresa Urbano
    • Antonio Lorenzon

  • PubMed: 41815197
  • DOI: 10.3746/pnf.2025.220

  2 Insights on

  • Reduced Squamous Cell Carcinoma

  • High evidence
  • Mixed

  niacinamide supplementation reduced the incidence of basal and squamous cell carcinoma (the major subtypes of non-melanoma skin cancer)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes