Vitamin B3 and Reduced Squamous Cell Carcinoma Incidence

• Chemoprevention of keratinocyte carcinomas and actinic keratoses in adults who were immunocompetent: a systematic review.

  • 2026-02-11
  • Systematic Review · n = 7,355
  • Clinical and experimental dermatology 51(7)
  • • Alyssa Susanto
    • Emma Morgan
    • Daniel Lindsay
    • Louisa G Collins

  • PubMed: 41671392
  • DOI: 10.1093/ced/llag073

  2 Insights on

  • Reduced Squamous Cell Carcinoma Incidence

  • High evidence
  • Clinical

  Nicotinamide reduced SCCs by 30% and AKs by 13-35% across two trials (P < 0.05).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes