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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin B6 and Reduced Anxiety

Doses used in studies

mg/day: 80 (median 80, IQR 80–80) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression.
- 2022-07-19
- RCT · n = 307
- Human psychopharmacology 37(6)
- - David T Field
  - Rebekah O Cracknell
  - Jessica R Eastwood
  - Peter Scarfe
  - Claire M Williams
  - Ying Zheng
  - Teresa Tavassoli
- PubMed: 35851507
- DOI: 10.1002/hup.2852
5 Insights on
- Reduced Anxiety
- High evidence
- Large Human Trial
- Adults
Vitamin B12 supplementation produced trends towards changes in anxiety
Effect
Neutral
Effect size
Small
Significant
No
Dose
high-dose
Effect of vitamin B6 on pain, disease severity, and psychological profile of fibromyalgia patients; a randomized, double-blinded clinical trial.
- 2022-07-13
- RCT · n = 90
- BMC musculoskeletal disorders 23(1)
- - Banafsheh Ghavidel-Parsa
  - Arvin Naeimi
  - Faeze Gharibpoor
  - Nazila Sattari
  - Atefeh Jafari
  - Irandokht Shenavar Masooleh
  - Ali Montazeri
- PubMed: 35831850
- DOI: 10.1186/s12891-022-05637-7
3 Insights on
- Reduced Anxiety
- High evidence
- Clinical
there was no statistically significant intergroup difference regarding primary outcomes
Effect
Neutral
Effect size
Small
Significant
No
Dose
80 mg daily