Vitamin B9 and Improved Folate Level

• Profile of neural tube defects in pediatric patients in Nigeria: A systematic review.

  • 2026-03
  • Systematic Review · n = 390
  • Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 145
  • • Nicholas Kendall
    • Joshua Woo
    • Brady K Browning
    • Oluwafemi Owagbemi
    • Temitayo O Ayantayo
    • Sean C Holden-Kapshuck
    • Haley G Kieny
    • Zoey Petitt
    • Megan E H Still
    • Elizabeth Blackwood
    • Bamidele O Adebayo
    • Olawale A R Sulaiman
    • Muhammad R Mahmud
    • Amos O Adeleye
    • Matthew T Shokunbi
    • Michael M Haglund
    • Alvan-Emeka K Ukachukwu

  • PubMed: 41500170
  • DOI: 10.1016/j.jocn.2026.111853

  2 Insights on

  • Improved Folate Level

  • High evidence
  • Clinical

  Folate usage improved from 12.5% (1990-99) to 60.9% (2020-23).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes