Vitamin B9 and Improved Renal Function

• The potential adding therapeutic effect of pentoxifylline and/or folic acid for chronic kidney disease patients: randomized controlled trial.

  • 2025-08-18
  • RCT · n = 80
  • BMC nephrology 26(1)
  • • Amira Reda Muhammad Galal
    • Nahla Mohamed Teama
    • Karema Abu-Elfotuha
    • Ahmed D Alatawi
    • Hanan Alshareef
    • Ahmed M E Hamdan
    • Ahmed Aljabri
    • Mohannad Alshibani
    • Zeinab AlKasaby Mahmoud Zalat

  • PubMed: 40826392
  • DOI: 10.1186/s12882-025-04399-3

  2 Insights on

  • Improved Renal Function

  • High evidence
  • Clinical

  There was a significant improvement in renal function biochemical parameters and a significant reduction in the FAS for the intervention groups compared to the control group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  therapeutic dose

• A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review.

  • 2026-05-01
  • Review
  • Medicine 105(18)
  • • Xuxia Cui
    • Yajing Zhong
    • Chongjuan Yin

  • PubMed: 42065149
  • DOI: 10.1097/md.0000000000048340

  4 Insights on

  • Improved Renal Function

  • Low evidence
  • Infants

  At discharge, the patient exhibited stable vital signs, improved developmental milestones, reduced pulmonary artery systolic pressure, normal renal function, and no evidence of hydrocephalus progression.

  Effect

  Beneficial

  Effect size

  Moderate