Vitamin B9 and Reduced Obesity

• Folate and global health umbrella review series, part 1: methodological framework and syntheses on anaemia and neural tube defects.

  • 2026-01-30
  • Systematic Review
  • Journal of global health 16
  • • Samantha Yoo
    • Azita Montazeri
    • Derrick Bennett
    • Yacong Bo
    • Peizhan Chen
    • Susan Duthie
    • Natalie Jensen
    • Atipatsa Kaminga
    • Jun-Shi Lai
    • Xue Li
    • Amanda J MacFarlane
    • Homero Martinez
    • Helene McNulty
    • Franco Momoli
    • Peter Mossey
    • Patrick Mullie
    • Ron Munger
    • Rajendra Prasad Parajuli
    • Monique Potvin Kent
    • Michele Rubini
    • Marjanne Senekal
    • Lindsey Sikora
    • Alain Stintzi
    • Evropi Theodoratou
    • Hui Wang
    • Chittaranjan Yajnik
    • Ann Yaktine
    • Julian Little

  • PubMed: 41612855
  • DOI: 10.7189/jogh.16.04014

  2 Insights on

  • Reduced Obesity

  • High evidence

  Maternal folic acid use was also significantly inversely related to the prevention of NTD at birth (RR = 0.31; 95% CI = 0.16, 0.60; I² = 0%) and NTD recurrence (RR = 0.30; 95% CI = 0.14, 0.65; I² = 0%)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Active folates and choline in prenatal development: current recommendations and clinical implications.

  • 2026-02-27
  • Review
  • Ginekologia polska 97(2)
  • • Aleksandra Krupa
    • Violetta Skrzypulec-Plinta

  • PubMed: 41432531
  • DOI: 10.5603/gpl.105802

  1 Insight on

  • Reduced Obesity

  • Low evidence

  Folate supplementation is universally recommended to reduce the risk of NTDs

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  0.4 to 0.8 mg daily