Vitamin B9 and Reduced Risk of Colorectal Cancer

• Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer.

  • 2025-01-29
  • Meta-Analysis
  • BMC cancer 25(1)
  • • Meng Ye
    • Guojie Xu
    • Liming Zhang
    • Zhihui Kong
    • Zhenhua Qiu

  • PubMed: 39875876
  • DOI: 10.1186/s12885-025-13546-w

  1 Insight on

  • Reduced Risk of Colorectal Cancer

  • High evidence
  • Clinical

  Amount folate intakes might reduce the morbidity of CRC for people in MTHFR 677TT genotype (OR = 0.68; 95% CI: 0.48,0.96; P = 0.03).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes