Vitamin B9 and Reduced Suicide-Related Endpoints

• The relationship between vitamin B9 (folate) supplementation and suicidality: a scoping review.

  • 2026-06
  • Review · n = 475
  • The mental health clinician 16(3)
  • • Chris Noel
    • Nick Lombardi
    • Michelle Price
    • Erik Herbert
    • Jill E Lavigne

  • PubMed: 42239831
  • DOI: 10.9740/mhc.2026.06.150

  2 Insights on

  • Reduced Suicide-Related Endpoints

  • High evidence
  • Mixed

  The randomized controlled trial and the other case-control study reported no significant benefit for suicide-related endpoints.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  1 to 5 mg/day