Vitamin C and Improved Overall Survival

• Overall and Progression-Free Survival of Patients With Malignant Neoplasm Following Intravenous Vitamin C: A Systematic Review and Meta-Analysis.

  • 2025-07-01
  • Meta-Analysis
  • International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 95(3)
  • • Jinxiu Qu
    • Mingtao Yao
    • Shijie Yu
    • Yi Wang
    • Shuai Lu
    • Bing Wang
    • Jia He
    • Shiwan Wang
    • Yuan Zhao
    • Xin Wang
    • Xiaomei Tao
    • Xiaozhu Liu
    • Yizhong Rao
    • Yuru Li
    • Benqiang Rao

  • PubMed: 40613397
  • DOI: 10.31083/ijvnr37372

  2 Insights on

  • Improved Overall Survival

  • High evidence
  • Clinical

  Intravenous vitamin C was associated with a significantly longer median overall survival (pooled estimated median survival ratio: 1.83; 95% confidence interval: 1.40-2.40; p < 0.001; moderate certainty)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  2.5 g/d to 1.5 g/kg of body weight per day